Synaptic Function, Dysfunction and Repair Workshop
Monday 1st April 2019, 2.00pm – Tuesday 2nd April 2019, 1.00pm
Auditório Professor Manuel Machado Macedo
CEDOC-NOVA Medical School|Faculdade de Ciências Médicas
Universidade NOVA de Lisboa
This event aims to showcase the work of the UCL and Portuguese community in the fields of Synaptic Function, Dysfunction and Repair with a view to fostering closer ties and facilitating collaborations.
The programme will explore novel aspects of synaptic structure and function, and how these aspects are compromised in major neurodegenerative pathologies, such as Alzheimer’s disease and motor neuron disease. Mechanisms responsible for synaptic recovery and de novo synaptogenesis will be also included. The programme will comprise of oral presentations from researchers at UCL as well as the Discoveries Centre partner universities. This exciting event will provide a great opportunity to network with fellow researchers and clinicians and will include an evening drinks reception on the first night.
Day 1 – Monday 1st April 2019
1.30pm – Registration
2.00pm – Professor Giampietro Schiavo, University College London, Welcome and Opening Address - The Discoveries Centre for Regenerative & Precision Medicine
2.10pm – Session 1: Synaptic Function
2.10pm – Talk 1: Professor Miguel Seabra, Universidade NOVA de Lisboa, Cellular ageing and chronic disease: mechanisms and interventions
2.40pm – Talk 2: Rita Teodoro, CEDOC, Universidade NOVA de Lisboa, Neuronal membrane blebbing as a novel mechanism of activity-dependent bouton formation
3.10pm – Talk 3: Mónica Sousa, IBMC, The regulation axonal contractility and propagation velocity
3.40pm – Talk 4: João Relvas, IBMC, Talk Title TBC
4.10pm – tea/coffee break & exhibit TBC
4.40pm – Session 2: Synaptic Dysfunction and Repair
4.40pm – Talk 1: Dr Marc Busche, UK Dementia Research Institute, University College London, Circuit changes underpinning progression in Alzheimer’s disease
5.10pm – Talk 2: Cláudia Almeida, CEDOC, Universidade NOVA de Lisboa, Impact of late-onset Alzheimer’s disease risk factors on synapses
5.40pm – Talk 3: Miguel Oliveira, Univ Minho, Nanobiomaterials advances for the Central Nervous System and Peripheral Nerve Regeneration
6.10pm – Closing remarks and questions
6.30-7.30pm – Evening Reception
Day 2 – Tuesday 2nd April 2019
9.00am – Tea & Coffee
9.30am – Session 3: Synaptic Dysfunction and Repair
9.30am – Talk 1: Professor Stephanie Schorge, UCL School of Pharmacy, Brain Hacking with Viruses: Gene therapy for epilepsy
10.00am – Talk 2: Catarina Brito, ITQB, Universidade NOVA de Lisboa & IBET, Modelling neuronal microenvironment dynamics in disease
10.30am – Talk 3: Helena Vieira, CEDOC, Universidade NOVA de Lisboa, Targeting microglia for the improvement of neuronal function
11.00am – Coffee Break
11.30 – Session 4: Synaptic Function
11.30am Talk 1: Vanessa Morais, IMM, Synaptic mitochondria: In search of its functional fingerprint
12.00pm – Talk 2: Teresa Summavielle, Universidade do Porto, Psychostimulant-elicited synaptic modulation through regulation of Cdc42
12.30pm – Talk 3: Odete Cruz e Silva, Universidade de Aveiro, Protein phosphatases and the synapse
1.00pm – Closing remarks and Farewell
1.05pm – Lunch
Registrations and further information online.
The event is free but the registrations are limited.
Programme and Abstract Book available here.