2019

Ana S. Brandão, Anabela Bensimon-Brito, Raquel Lourenço, Jorge Borbinha, Ana Rosa Soares, António Jacinto. Yap induces osteoblast differentiation by modulating Bmp signalling during zebrafish caudal fin regeneration. Journal of Cell Science 2019 : jcs.231993 doi: 10.1242/jcs.231993

Mendes C, Lopes-Coelho F, Ramos C, Martins F, Santos I, Rodrigues A, Silva F, André S, Serpa J. Unraveling FATP1, regulated by ER- as a targeted breast cancer innovative therapy, Scientific reports 2019, Oct 1;9(1):14107. doi: 10.1038/s41598-019-50531-3.

Casalou C, Faustino A, Silva F, Ferreira IC, Vaqueirinho D, Ferreira A, Castanheira P, Barona T, Ramalho JS, Serpa J*, Félix A*, Barral DC. Arl13b Regulates Breast Cancer Cell Migration and Invasion by Controlling Integrin-Mediated Signaling, Cancers 2019, Sep 29;11(10). pii: E1461. doi: 10.3390/cancers11101461. *Equal contribution

Mota P, Pires RF, Serpa J, Bonifácio VDB. L-Buthionine Sulfoximine Detection and Quantification in Polyurea Dendrimer Nanoformulations. Molecules. 2019, Aug 27;24(17). pii: E3111. doi: 10.3390/molecules24173111

Nunes J, Charneira C, Nunes C, Gouveia-Fernandes S, Serpa J, Morello J, Antunes AMM. A Metabolomics-Inspired Strategy for the Identification of Protein Covalent Modifications. Frontiers in Chemistry. 2019 Jul 31;7:532. doi: 10.3389/fchem.2019.00532.

Lopes-Coelho F, Silva F, Hipólito A, Cardoso BA, Serpa J. Acetylation drives hepatocyte nuclear factor 1 stability by blocking proteasome-mediated degradation. Journal of Cellular Biochemistry. 2019 Jun;120(6):9337-9344 doi: 10.1002/jcb.28209

Melo A, Matias MA, Dias SS, Gregório MJ, Rodrigues AM, de Sousa RD, Canhão H, Perelman J. Is food insecurity related to health-care use, access and absenteeism? Public Health Nutr. 2019 Aug 6:1-9. doi: 10.1017/S1368980019001885. [Epub ahead of print]

Rodrigues AM, Eusébio M, Rodrigues AB, Caetano-Lopes J, Lopes IP, Lopes A, Mendes JM, Coelho PS, Fonseca JE, Branco JC, Canhão H. Low Serum Levels of DKK2 Predict Incident Low-Impact Fracture in Older Women. JBMR Plus. 2019 Mar 28;3(7):e10179. doi: 10.1002/jbm4.10179. eCollection 2019 Jul.

Torre C, Guerreiro J, Mendes Z, Miranda A, Bragança F, Cristino J, Canhão H, Branco JC. Low persistence with oral biphosphonate treatment in postmenopausal osteoporosis. Acta Reumatol Port. 2019 Apr-Jun;44(2):114-125.

Maia I, Monjardino T, Frias B, Canhão H, Branco JC, Lucas R, Santos AC. Food Insecurity in Portugal Among Middle- and Older-Aged Adults at a Time of Economic Crisis Recovery: Prevalence and Determinants. Food Nutr Bull. 2019 Jul 4:379572119858170. doi: 10.1177/0379572119858170. [Epub ahead of print]

Canhao H, Masuko K, Nakamura H. Editorial: Nutrition and Metabolism in Rheumatic Diseases. Front Med (Lausanne). 2019 May 8;6:101. doi: 10.3389/fmed.2019.00101. eCollection 2019. No abstract available.

Sanmarti R, Veale DJ, Martin-Mola E, Escudero-Contreras A, González C, Ercole L, Alonso R, Fonseca JE; ToSpace Study Group. Reducing or Maintaining the Dose of Subcutaneous Tocilizumab in Patients With Rheumatoid Arthritis in Clinical Remission: A Randomized, Open-Label Trial. Arthritis Rheumatol. 2019 Oct;71(10):1616-1625. doi: 10.1002/art.40905. Epub 2019 Sep 24.

Castelo-Branco L, Silva IP, Canhão H, Awada A. Promising Immuno-Oncology Treatments Beyond the 2018 Nobel Prize. Acta Med Port. 2019 Apr 30;32(4):251-257. doi: 10.20344/amp.12040. Epub 2019 Apr 30. No abstract available.

Spiliopoulou A, Colombo M, Plant D, Nair N, Cui J, Coenen MJ, Ikari K, Yamanaka H, Saevarsdottir S, Padyukov L, Bridges SL Jr, Kimberly RP, Okada Y, van Riel PLC, Wolbink G, van der Horst-Bruinsma IE, de Vries N, Tak PP, Ohmura K, Canhão H, Guchelaar HJ, Huizinga TW, Criswell LA, Raychaudhuri S, Weinblatt ME, Wilson AG, Mariette X, Isaacs JD, Morgan AW, Pitzalis C, Barton A, McKeigue P. Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40and CD39. Ann Rheum Dis. 2019 Aug;78(8):1055-1061. doi: 10.1136/annrheumdis-2018-214877. Epub 2019 Apr 29.

Oliveira P, Zejnilovic L, Azevedo S, Rodrigues AM, Canhão H. Peer Adoption and Development of Health Innovations by Patients: National Representative Study of 6204 Citizens. J Med Internet Res. 2019 Mar 26;21(3):e11726. doi: 10.2196/11726.

Canet LM, Sánchez-Maldonado JM, Cáliz R, Rodríguez-Ramos A, Lupiañez CB, Canhão H, Martínez-Bueno M, Escudero A, Segura-Catena J, Sorensen SB, Hetland ML, Soto-Pino MJ, Ferrer MA, García A, Glintborg B, Filipescu I, Pérez-Pampin E, González-Utrilla A, Nevot MÁL, Conesa-Zamora P, den Broeder A, De Vita S, Jacobsen SEH, Collantes-Estevez E, Quartuccio L, Canzian F, Fonseca JE, Coenen MJH, Andersen V, Sainz J. Correction: Polymorphisms at phase I-metabolizing enzyme and hormone receptor loci influence the response to anti-TNF therapy in rheumatoid arthritis patients. Pharmacogenomics J. 2019 Feb 14. doi: 10.1038/s41397-019-0084-2. [Epub ahead of print]

Cracchiolo M, Sacramento JF , Mazzoni A, Panarese A , Carpaneto J,Conde SV,* Micera S*. Decoding neural metabolic markers from the carotid sinus nerve in a type 2 diabetes model, 2019. doi: 10.1109/TNSRE.2019.2942398 (in press). * Shared last autorship

Figueiredo-Pereira C, Menezes R, Ferreira S, N. Santos C and Vieira HLA. Carbon Monoxide Released by CORM-A1 Prevents Yeast Cell Death via Autophagy Stimulation. 2019 July 25. pii: foz051. doi: 10.1093/femsyr/foz051.

Osório DN, Viana-Soares R, Marto JP, Mendonça MD, Silva HP, Quaresma C, Viana-Baptista M, Gamboa H and Vieira HLA. Autonomic nervous system response to remote ischemic conditioning: heart rate variability assessment. 2019. doi: 10.1186/s12872-019-1181-5

Sacramento JF, Olea E, Ribeiro MJ, Prieto-Lloret J, Melo BF, Gonzalez C, Martins FO, Monteiro EC, Conde SV.Contribution of adenosine and ATP to the carotid body chemosensory activity in ageing. J Physiol. 2019 Aug 19. doi: 10.1113/JP274179.

Heleno B, Rodrigues DS. Multimorbidity and the Challenge to Deliver Personalised and Meaningful Health Care. Port J Public Health, 1:3. Doi: 10.1159/000502270

Lapao L, Pisco L. A reforma da atenção primária à saúde em Portugal, 2005-2018: o futuro e os desafios da maturidade. Cad. Saúde Pública 2019; 35 Sup 2:e00042418. Doi: 10.1590/0102-311X00042418

Kuhns S, Seixas C, Pestana S, Tavares B, Nogueira R, Jacinto R, Ramalho JS, Simpson JC, Andersen JS, Echard A, Lopes SS, Barral DC, Blacque OE. Rab35 controls cilium length, function and membrane composition. EMBO Rep. 2019 Aug 21:e47625. doi: 10.15252/embr.201847625.

Burkhalter MD, Sridhar A, Sampaio P, Jacinto R, Burczyk MS, Donow C, Angenendt M; Competence Network for Congenital Heart Defects Investigators, Hempel M5, Walther P, Pennekamp P, Omran H, Lopes SS, Ware SM, Philipp M. Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis. J Clin Invest. 2019 May 16;130:2841-2855. doi: 10.1172/JCI98890.

Lozza L, Moura-Alves P, Domaszewska T, Lage Crespo C5 Streata I, Kreuchwig A, Puyskens A, Bechtle M, Klemm M, Zedler U, Silviu Ungureanu B, Guhlich-Bornhof U, Koehler AB, Stäber M, Mollenkopf HJ, Hurwitz R, Furkert J, Krause G, Weiner J, Jacinto A, Mihai I, Leite-de-Moraes M, Siebenhaar F, Maurer M, Kaufmann SHE. The Henna pigment Lawsone activates the Aryl Hydrocarbon Receptor and impacts skin homeostasis. Sci Rep. 2019 Jul 26;9(1):10878. doi: 10.1038/s41598-019-47350-x.

Hayes MJ, Burgoyne T, Wavre-Shapton ST, Tolmachova T, Seabra MC, Futter CE. Remodeling of the Basal Labyrinth of Retinal Pigment Epithelial Cells With Osmotic Challenge, Age, and Disease. Invest Ophthalmol Vis Sci. 2019 Jun 3;60(7):2515-2524. doi: 10.1167/iovs.19-26784.

Storck EM, Morales-Sanfrutos J, Serwa RA, Panyain N, Lanyon-Hogg T, Tolmachova T, Ventimiglia LN, Martin-Serrano J, Seabra MC, Wojciak-Stothard B, Tate EW. Dual chemical probes enable quantitative system-wide analysis of protein prenylation and prenylation dynamics. Nat Chem. 2019 Jun;11(6):552-561. doi: 10.1038/s41557-019-0237-6. Epub 2019 Apr 1.

Sanzà P, Evans RD, Briggs DA, Cantero M, Montoliu L, Patel S, Sviderskaya EV, Itzen A, Figueiredo AC, Seabra MC, Hume AN. Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a. J Cell Sci. 2019 Apr 30;132(9). pii: jcs212035. doi: 10.1242/jcs.212035.

Moreiras H, Lopes-da-Silva M, Seabra MC, Barral DC. Melanin processing by keratinocytes: A non-microbial type of host-pathogen interaction? Traffic. 2019 Apr;20(4):301-304. doi: 10.1111/tra.12638.

Rodrigues D, Dias CV, Heleno B. Como responder a dúvidas clínicas. Revista Portuguesa de Medicina Geral e Familiar, [S.l.], v. 35, n. 2, p. 155-66, maio 2019. ISSN 2182-5181.

Silvério Rodrigues D, Sousa PF, Basílio N, et al. Primary care physicians’ decision-making processes in the context of multimorbidity: protocol of a systematic review and thematic synthesis of qualitative research. BMJ Open 2019;9:e023832. doi: 10.1136/bmjopen-2018-023832

Ponte S, Jacinto A, Carvalho L. The occluding junction protein Neurexin-IV is required for tissue integrity in the Drosophila wing disc epithelium. Matters. Apr 5, 2019. DOI 10.19185/matters.201903000014

Viegas Dias C, Maria AR, Dias AC, Heleno B. Evidence‐based brunch to practise literature appraisal skills. Med Educ [Internet]. 2019 Mar 15

Hoffmann AC, Minakaki G, Menges S, Salvi R, Savitskiy S, Kazman A, Vicente Miranda H, Mielenz D, Klucken J, Winkler J, Xiang W. (2019) Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose. Sci Rep. 2019 Jan 24;9(1):544. doi: 10.1038/s41598-018-35811-8.

Canhão, H., Branco, J. C., Liotta, G., eds. (2019). Active Aging and Disease Management. Lausanne: Frontiers Media. doi: 10.3389/978-2-88945-681-9