With the coronavirus pandemic the Chronic Diseases Research Centre, from NOVA Medical School, has put in place a number of measures and redirected its main research activities to diagnosis work to help the global efforts to fight COVID-19.
Diagnosis by PCR
Standard Operating Procedure (SOPs) of the Diagnosis by PCR
Volunteers of Diagnosis by PCR Team
Protocol with Santa Casa da Misericórdia de Lisboa
NOVA Medical School signed a protocol with Santa Casa da Misericórdia de Lisboa regarding the diagnostic tests of SARS-CoV-2 conducted by CEDOC-NMS to the users of the Homes of Santa Casa da Misericórdia de Lisboa.
Serology4COVID Consortium aims to develop of a serological test for the Portuguese population. This joint effort is crucial to combat the impact of the SARS-CoV-2 virus on society.
This Consortium comprises 5 scientific research institutes in the Lisbon-Oeiras area, namely CEDOC-NMS, iBET - Instituto de Biologia Experimental e Tecnológica, IGC - Instituto Gulbenkian de Ciência, iMM - Instituto de Medicina Molecular and ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier.
The initiative is supported by the COVID-19 Emergency Fund of Fundação Calouste Gulbenkian, of Sociedade Francisco Manuel dos Santos and of Câmara Municipal de Oeiras.
More information regarding Serology4COVID Consortium in the press release (portuguese).
Helena Soares e Juliana Gonçalves
NOVA University is using these serological tests to test the NOVA academic community for COVID-19. Info at NOVA website.
Alternative Diagnosis Test by PCR
Vasco Barreto is leading a project, funded by FCT and ANI, entitled “Ultra-sensitive, specific, scalable, fast and cheap: a colorimetric-assisted single-tube nested conventional PCR to detect the Sars-Cov-2 RNA in nasopharyngeal swabs”.
This initiative aims to replace the current qPCR-based method to test infection of the new coronavirus used in Portugal, allowing to increase up to an order of magnitude the installed capacity of the many Portuguese research units from the SciPTaskForce COVID-19.
The new testing method that is being developed by Vasco Barreto and his team presents several advantages, such as being simpler, lower-priced, designed for a regular thermocycler and should have increased sensitivity. In addition to this, removing the bottlenecks that currently limit testing, namely RNA isolation and the need for a rare qPCR machine, would scale up the installed capacity of the Portuguese research units by at least a factor of six, while lowering the cost price of a single test.
Vasco Barreto, Vasco Barreto Lab and Fabiana Herédia
Partnering with Maria João Amorim, from IGC - Instituto Gulbenkian de Ciência.
Eng. Miguel Valadas
COLife is an alliance of six research institutes in life sciences located in Lisbon and Oeiras: Chronic Diseases Research Centre - NOVA Medical School (CEDOC-NMS), Champalimaud Research - Fundação Champalimaud, Instituto de Biologia Experimental e Tecnológica (iBET), Instituto de Medicina Molecular João Lobo Antunes (iMM), Instituto de Tecnologia Química e Biológica António Xavier da Universidade NOVA de Lisboa (ITQB NOVA) and Instituto Gulbenkian de Ciência (IGC) - More info at COLife website
Scientists from COLife institutes are dedicating their efforts and knowledge to understand, translate, and improve communication on COVID-19 to a broad audience, ranging from peers (other researchers, medical doctors and health professionals) to politicians and civil society.
COLife Science Digests assembles up-to-date research findings, from all over the world, reviewed by COLife scientists, edited and translated by COLife science communicators.
Live Webinars | Sharing Information Together:
Webinar II - Como aceder a informação fidedigna?
Webinar III - Vamos falar de vacinas?
Other Initiatives by CEDOC and NMS professionals
Other Initiatives by NOVA: