CEDOC - CHRONIC DISEASES RESEARCH CENTRE - IS AN ESTABLISHED CENTRE WHICH AIMS AT EXCELLENCE IN MEDICAL RESEARCH ON CHRONIC DISEASES.
The general objectives of CEDOC are to form an internationally-recognized Center of excellence in Biomedical, Translational and Clinical Research on chronic diseases; to stimulate collaborative research between groups within the CEDOC; to strengthen research quality and innovation and to promote multidisciplinary projects within and beyond the Center; to provide an exciting research environment for the training of Postdoctoral Fellows, PhD and Master funding at national and international levels; and to simulate the organization of outreach activities at local and national levels.
CEDOC’s Biomedical research groups are multidisciplinary in nature, using existing knowledge from basic research and methodically expanding it to address a specific medical problem. The Biomedical Research they produce is oriented to understanding the causes of disease of various chronic pathologies, from diabetes and cancer to rare autoimmune diseases.
- Cancer Metabolism and Microenvironment | Jacinta Serpa
- Cilia Regulation & Disease | Susana Lopes
- Cell Death & Disease | Helena Vieira
- Cellular and Systems Neurobiology | Rosalina Fonseca
- Computational and Experimental Biology | Rune Matthiesen
- DNA Breaks | Vasco Barreto
- DysBrainD: Dysmetabolism in Brain Diseases | Hugo Vicente Miranda
- Gene Therapy | Gabriela Silva
- Human Immunobiology and Pathogenesis | Helena Soares
- Inflammation and Neurodegeneration | Raffaella Gozzelino
- Integrative Biomedicine | Alisson Gontijo
- Lysosomes in Chronic Human Pathologies & Infection | Otilia Vieira
- MEDIR: Metabolic Disorders | M. Paula Macedo
- Membrane Traffic in Disease | Duarte Barral
- Molecular Mechanisms of Disease | Miguel Seabra
- Molecular Nutrition and Health | Cláudia N. Santos
- Neurogenetics of Locomotion | César Mendes
- Neuronal Control of Metabolic Disturbances: Therapeutic Strategies | Sílvia V. Conde
- Neuronal Growth and Plasticity | Rita Teodoro
- Neuronal Trafficking in Aging | Cláudia Almeida
- Proliferation and Fate Regulation of Stem Cells | Catarina Homem
- Proteostasis and Proteolytic Signalling | Paulo Pereira
- Stem Cells and Development | José Belo
- Tissue Repair and Inflammation | António Jacinto
- Translational Pharmacology | Emília Monteiro
- Tumor Morphology and Microenvironment | Ana Félix
Biomedical Resources & Services
Clinical Resources & Services
Rare Diseases' Research
Twinning project LYSOCIL aims to strengthen the research and innovation capacity of CEDOC and NMS|FCM, on the field of rare diseases, namely lysosomal diseases and ciliopathies. As such, several dissemination actions are being developed, including exchanges, workshops, retreats, and other activities aimed towards clinicians, patients and family members, patient associations and researchers, together with Munster University (WWU) and Telethon Institute of Genetics and Medicine (TIGEM).
To know more about LYSOCIL project visit the project website.
CEDOC’s Clinical Research is conducted across the institute and its affiliated hospitals by Clinicians and Biomedical researchers. The main objective is to promote new therapeutic strategies, with considerable impact in public health.
- Allergy, Immunodeficiency and Translational Immunology | Luis Miguel Borrego
- EpiDoc Unit | Helena Canhão
- Immune Response & Vascular Disease | José Alves
- Mental Health Needs & Interventions | Miguel Xavier
- Neurology: Stroke & Dementia | Miguel Viana Baptista
- Person-centred Care Research | Bruno Heleno
- Psychiatric Epidemiology & Liaison Psychiatry | José Caldas de Almeida
- Integrated Pathophysiological Mechanisms | Nuno Neuparth
- Rheumatic Diseases | Fernando Pimentel
The Comprehensive Health Research Centre (CHRC) is a multidisciplinary, multi-institutional and comprehensive new research centre aimed at supporting, developing and fostering clinical, public health and health services research. The other CHRC pillars and central activities are health education and training; innovation, digital and entrepreneurship.
CHRC presentation video by CHRC Coordinator, Helena Canhão.
iNOVA4Health is a translational medicine programme organizing the efforts of biomedical researchers involved in i) biological understanding of disease, lead compounds and biopharmaceuticals pre-discovery, ii) technological scientists involved in preclinical development, and iii) clinicians involved in early clinical and first-in-man clinical trials from institutions within NOVA University of Lisbon. The programme will have a strong emphasis on developing therapies to promote healthy ageing and in targeting chronic diseases that are responsible for two thirds of deaths worldwide and a major burden on healthcare systems.
ToxOmics is a research unit that aims to carry out innovative research and advanced education and training towards a better assessment of genetics as a determinant of health - interaction between genes, environmental stress and disease causation - allowing more accurate disease prediction and prevention as well as more effective therapeutic interventions.
Interdisciplinary R&D activities use genomic and post-genomic methodologies to study the molecular, biochemical and cellular aspects of human genetic disorders and environmental stress through four interrelated approaches (i) exposure assessment and biological responses to stressors, (ii) variability in gene expression and regulation in the disease process and (iii) evaluation and development of toxicogenomic and toxicoproteomic biomarkers.